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The Substance
R
141 minutes | 
English
Playing at GlendaleNoHo 7Town Center 5Newhall
Coming to Firehouse Theater on 10.18.24
Now Playing
Demi Moore gives a career-best performance as Elisabeth Sparkle, a former A-lister "past her prime" and fired from her fitness TV show by the repellent studio head (Dennis Quaid). She is drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection and she is reborn – temporarily – as the twentysomething Sue (Margaret Qualley). The only rule? You are one, and time needs to be split: one week in one body, one week in the other. What could go wrong?