LITTLE JOE follows Alice, a single mother and dedicated senior plant breeder at a corporation engaged in developing new species. She has engineered a special crimson flower, remarkable not only for its beauty but also for its therapeutic value: if kept at the ideal temperature, fed properly and spoken to regularly, this plant makes its owner happy. Against company policy, Alice takes one home as a gift for her teenage son, Joe. But as their plant grows, so too does Alice’s fear that her new creation may not be harmless.