How does a man who is literally paralyzed by happiness find love? Thanks to a condition called cataplexy—a rare disorder that causes him to lose control of his muscles whenever he is overcome by strong emotion, particularly joy—Brooklyn librarian Charlie has learned to carefully edit all delight-triggering people, places, and events out of his life. But when the beautiful, spontaneous Francesca falls for him, the risk-averse Charlie finds himself at a crossroads: suppress his feelings of attraction, or take a chance and let love in?